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Wide application of silicone products in medical applications
As a high-performance material, silicone has broad application prospects in the medical field.
Due to its unique physical and chemical properties and excellent biocompatibility, silicone plays an important role in medical devices, prosthetic repair, wound dressings, drug delivery systems, dental applications, plastic surgery and prosthetics, artificial organs and auxiliary devices.
1. Medical device manufacturing
Silicone has become an ideal material for manufacturing high-precision medical devices due to its good biocompatibility and high temperature and corrosion resistance. For example, the use of silicone encapsulation technology in ultrasonic scalpels, staplers and other instruments used in minimally invasive cardiovascular surgery can not only improve the accuracy and safety of surgery, but also reduce the risk of infection. In addition, silicone is also widely used in medical devices such as infusion sets and catheters. Its softness and elasticity effectively avoid damage to human tissues and improve patient comfort.
2.Prosthesis and repair materials
Silicone is widely used in prosthesis and repair materials. In plastic surgery, silicone prostheses are widely used in rhinoplasty, breast augmentation and other surgeries. They are highly plastic and stable, can remain in the human body for a long time, and do not cause much harm to the human body. At the same time, silicone can also be used to make medical implants such as artificial joint gaskets and pacemaker electrodes to improve the durability of the product and reduce rejection reactions. In the field of repair, silicone is also used to repair tissue deformities or depressions and defects, such as artificial breasts and auricles.
3.Silicone wound dressing
Silicone wound dressing is an important medical product, consisting of an absorption layer, a gel layer and a peeling film. It can fit the wound surface tightly, protect the wound surface from external contamination, and absorb exudate to promote wound healing. Silicone wound dressing has good air permeability and can maintain a moist environment on the wound surface, which is conducive to cell growth and repair. In addition, silicone dressing can also reduce scar formation, bringing better recovery effects to patients
4.Medicine delivery systems
Silica gel also plays an important role in drug delivery systems. Through silica gel encapsulation technology, drugs can be closely combined with silica gel materials to form a stable solid dispersion. This drug delivery system has the effect of improving drug solubility, bioavailability and stability. At the same time, the silica gel material itself meets the requirements of the pharmacopoeia and has strong scalability, which can meet the needs of different drug delivery.
5.Silicone products in dental applications
In the dental field, silicone materials are widely used because of their softness and flexibility. Superfluid silicone, as a special silicone material, can flow freely in the air and into very small spaces, making it very suitable for repairing teeth with composite resin structures and modeling during oral implant surgery. In addition, silicone is also used to make dental restoration materials such as braces and porcelain veneers to achieve the effects of dental beauty and orthodontics. Its excellent molding and modeling capabilities make the application prospects of silicone in the dental field even broader.
6.Silicone plastic surgery and repair
7. Silicone artificial organs
Silicone is widely used in the production of artificial organs due to its good biocompatibility and anti-aging properties. For example, organ substitutes such as artificial eyes, artificial larynx, and artificial lenses are all made of silicone. These artificial organs can replace damaged or missing natural organs and restore the patient's normal physiological functions. In addition, silicone can also be used to make tissue engineering products such as meninges, tendons, and joints, making important contributions to the development of the medical field.
8. Other medical applications of silicone products
In addition to the above applications, silicone rubber is also used in the field of biomedical engineering. It mainly includes the outer packaging materials of medical devices, medical electrodes, and biological implant sensors.
The intraperitoneal chemotherapy drug delivery device is a fully silicone implantable intraperitoneal chemotherapy catheter system. The device is made of medical silicone rubber and consists of a drug storage box and a catheter. Medical electrodes (plates) are in contact with the human body, so the material is required to be soft, comfortable, physiologically inert, non-toxic to the human body, non-irritating to the skin, and have good breathability. During use, it must also withstand high temperature and high pressure, solvent disinfection, and the performance is not affected. To meet the above requirements, silicone rubber is more suitable as a substrate.
Biosensors are widely used, not only showing a bright future in basic research, clinical medicine, food fermentation, environmental protection, etc., but also becoming possible in vivo applications. Among them, two types of biosensors - biomedical electrodes and implanted sensors are typical examples of in vivo applications. Biosensors for transplantation usually require a layer of packaging material on the outside to separate the surrounding physiological environment. Therefore, in vivo applications, especially biomedical devices implanted in the human body, place higher requirements on the reliability, durability, and biocompatibility of materials. Silicone rubber has the characteristics of good elasticity and good biocompatibility. Therefore, the silicone rubber layer outside the electrode can be very thin, and water and other small molecules can pass freely. This silicone rubber can be used as an outer packaging for a glucose-sensitive electrode to monitor and regulate the glucose level in the blood of diabetics.
9.The development direction of medical silicone rubber
With the development of biomedical engineering and tissue engineering, the requirements for material technology and performance are increasing. As far as silicone rubber is concerned, how to make it fully applied to bioengineering and tissue engineering is the main direction of future research. For example, biosensors are a biotechnology that has attracted much attention today. The miniaturization of biosensors and their adaptability to organisms will become important research topics related to artificial organs. As the main material of artificial organs, silicone rubber has great potential for future development. At present, the development of medical silicone rubber in my country is lagging behind. In order to accelerate the pace of development in the future, we should first establish an industrial production base for medical silicone materials; focus on breakthroughs in the performance and quality evaluation technology of medical silicone materials and devices implanted in the human body; expand the application field of silicone rubber; and promote the formation of a serialized, high-end, large-scale and standardized business model for medical silicone rubber materials in my country.
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